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U.S. Life Sciences Reports

A healthier funding environment, strong M&A and licensing activity, and expanding pharmaceutical manufacturing and R&D construction drove improving momentum for the life sciences sector in Q1 2026. While headwinds remain, these tailwinds should support a resurgence in the life sciences real estate sector.

Download Q1 2026 Report

For the data behind the commentary, download the full Q1 2026 U.S. Life Sciences Report.


Q1 2026 Life Sciences Key Trends

  • Demand was essentially flat in Q1, with net absorption of -23,600 square feet (sf). Tenant-in-the-market activity remains stable across major markets, with strong demand for cGMP space from pharmaceutical tenants. 

  • Asking rents averaged $65.48 per square foot (psf), down 3.4% year-over-year (YOY), though several markets posted rent growth. The overall vacancy rate rose 196 basis points (bps) to 23.6%, the smallest YOY increase in nearly three years. Sublease vacancy declined 10 bps YOY to 3.5%.
  • New deliveries slowed to 1.2 million square feet (msf), nearly one-fifth of the 5.4 msf delivered in Q1 2025. The new construction pipeline has shifted decisively toward build-to-suit (BTS) projects; 72% of inventory under construction is now BTS, and the speculative share is at a five-year low. 
  • R&D property sales totaled $2.1 billion, down 12% YOY. Despite the decline, investor interest is building, highlighted by Healthpeak's $600 million acquisition of Blackstone's South San Francisco portfolio, the largest alternative asset deal in Q1. 

  • Venture capital funding totaled $8.0 billion in Q1, up 15% YOY, with most capital flowing to later-stage companies. Average deal size rose to a record $20 million, as investors took greater interest in making large investments in established companies. The initial public offering (IPO) market strengthened, with eight IPO’s raising more than $2.3 billion, nearly matching the $2.8 billion total for all of 2025.

For the data behind the commentary, download the full Q1 2026 U.S. Life Sciences Report.

Q1 2026 U.S. LIFE SCIENCES MARKETBEAT
Access Q1 2026 commercial real estate results for the life sciences sector.
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